昆虫を用いて特殊な装置なしにワクチンやタンパク質製剤を生産する
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群馬大学大学院理工学府
教授
武田 茂樹
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感染症やガンを含む非感染疾患対策のために、ワクチンや最新のタンパク質製剤が求められています。しかしこれらの生産には、高度な培養装置や有毒な細胞成分を除く処理が必要です。遺伝子組換えカイコを利用すれば、培養装置のような特殊な装置なしにカイコを飼育するだけでワクチンが生産できます。ワクチンを含むマユは常温で保管でき、抽出したワクチンにはほとんど有毒な細胞成分(エンドトキシン)は含まれません。本研究では、遺伝子組換えカイコの応用技術を地方創生を支える基盤技術に育てることで、地域の伝統や資産をいかした農山村の活性化、地域の人材育成を目指しています。
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Production of vaccines and protein preparations using insects without special equipment
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Shigeki Takeda
Professor, Graduate School of Science and Technology, Gunma University
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Vaccines and the advanced protein preparations are required to infectious disease measures and to countermeasures for non-infectious diseases including cancer. Productions for these materials require advanced culture equipment and processing to remove toxic endotoxin. We apply transgenic silkworms for the production of vaccines without any special equipment such as advanced culture systems. Cocoons containing the vaccine can be stored at room temperature, and the extracted vaccine contains almost no toxic cellular components (endotoxins). We aim to revitalize agricultural villages utilizing traditions and cultivate local human resources by cultivating the application technology of transgenic silkworms to the basic technology that supports regional revitalization.